Isotopically Labeled Compounds
Medchemexpress LLC Zuclomiphene-d4 (citrate) | 2714316-71-7 | 99.0% | 1 MG
Zuclomiphene-d4 citrate is a deuterium-labeled Zuclomiphene citrate. It is a cis isomer and is orally active, exhibiting an antiestrogenic effect. It can reduce cholesterol levels and is suitable for research in endocrinology and metabolic diseases.
- Deuterium labeled compound
- Orally active
- Antiestrogenic effect
- Can reduce cholesterol levels
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Veratrole-d6 | 24658-24-0 | 98.7% | 5 MG
Veratrole-d6 is a deuterium-labeled form of Veratrole (1,2-Dimethoxybenzene), a compound found in plants that attracts pollinators. Its release exhibits a circadian rhythm, playing a role in plant reproduction, species differentiation, and interactions with pollinators. Deuteration can influence the pharmacokinetic and metabolic profiles of drugs, making labeled compounds like Veratrole-d6 valuable as tracers in drug development and research.
- Useful as a tracer in drug development
- Deuterium-labeled compound
- Supports research into pharmacokinetics and metabolic profiles
Medchemexpress LLC Zuclomiphene-d4 citrate | 2714316-71-7 | 99.0% | 5 MG
Zuclomiphene-d4 citrate is a deuterium-labeled Zuclomiphene citrate, a cis isomer of Clomiphene citrate. It is orally active and exhibits an antiestrogenic effect, capable of reducing cholesterol levels. It is used for research in endocrinology and metabolic disease.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Veratrole-d6 | 24658-24-0 | 98.7% | 100 MG
Veratrole-d6 is a deuterium-labeled version of Veratrole, also known as 1,2-Dimethoxybenzene. Veratrole is an important compound found in plants, playing a role in attracting pollinators. Its release follows a circadian rhythm and is crucial for plant reproduction, species differentiation, and interactions with pollinators. Additionally, Veratrole can undergo demethylation by cytochrome P-450 in *Streptomyces setonii*.
- Isotope-labeled compound
- Targets cytochrome P450
Medchemexpress LLC Maprotiline-d5 hydrochloride | 1794942-12-3 | 1 MG
Maprotiline-d5 hydrochloride is a deuterium-labeled version of Maprotiline hydrochloride, functioning as a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant. This compound is suitable for various quantitative analyses due to its stable heavy isotopes.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes for drug development tracing
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Sulfasalazine-d4 | 1346606-50-5 | 99.3% | 402.42 | 1 MG
Sulfasalazine-d4 is a deuterium-labeled version of Sulfasalazine, an anti-rheumatic agent used in the research of rheumatoid arthritis and ulcerative colitis. It is known to suppress NF-κB activity and functions as a type 1 ferroptosis inducer.
- Incorporates stable heavy isotopes as tracers
- Suitable for use as a tracer in various research applications
- Can be used as an internal standard for quantitative analytical techniques such as NMR, GC-MS, or LC-MS
Medchemexpress LLC Devimistat-d10 | 2586055-61-8 | C22H18D10O2S2 | 100 MG
Devimistat-d10 is the deuterium-labeled Devimistat. It is for research use only and not sold to patients. This compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium-labeled Devimistat
- For research use only
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC (Rac)-Rotigotine-d3 hydrochloride | 1215846-20-0 | C19H23D3ClNOS | 1 MG
(Rac)-Rotigotine-d3 hydrochloride is a deuterium labeled (Rac)-Rotigotine (hydrochloride), which is a racemate of Rotigotine. Rotigotine acts as a full agonist of the dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Ki values for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor ranging from 0.71 nM to 83 nM.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Functions as a full agonist of dopamine receptors.
- Acts as a partial agonist of the 5-HT1A receptor.
- Antagonizes the α2B-adrenergic receptor.
Medchemexpress LLC Yohimbine-d3 | 133146-00-6 | 99.36% | 1 MG
Yohimbine-d3 is a deuterium-labeled version of Yohimbine (HY-12715). This compound serves as a tracer and can be used as an internal standard for quantitative analysis through techniques like NMR, GC-MS, or LC-MS. Deuterium substitution in drug molecules is being explored for its potential to influence pharmacokinetic and metabolic profiles.
- Deuterium labeled yohimbine.
- Can be used as a tracer.
- Suitable as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration may impact pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Oxprenolol-d7 hydrochloride | 1189649-47-5 | 98.25% | 5 MG
Oxprenolol-d7 (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Oxprenolol-d7 hydrochloride | 1189649-47-5 | 98.3% | 1 MG
Oxprenolol-d7 (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle.
- Can be used as a tracer.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes as tracers for quantitation during drug development.
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Imipramine-d6 | 65100-45-0 | 500 UG
Imipramine-d6 is a deuterium-labeled Imipramine hydrochloride. Imipramine is an orally active tertiary amine tricyclic antidepressant, which acts as a Fascin1 inhibitor with antitumor activities and inhibits serotonin transporter with an IC50 value of 32 nM. It stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis, exhibiting neuroprotective and immunomodulatory effects.
- Used as a tracer for quantitation during drug development.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- May affect the pharmacokinetic and metabolic profiles of drugs due to deuteration.
- Fascin1 inhibitor with antitumor activities.
- Inhibits serotonin transporter (IC50 value of 32 nM).
- Stimulates U-87MG glioma cells autophagy.
- Induces HL-60 cell apoptosis.
- Shows neuroprotective effects.
- Exhibits immunomodulatory effects.
Medchemexpress LLC Robenidine-d8 (hydrochloride) | 1173097-77-2 | 99.0% | 5 MG
Robenidine-d8 hydrochloride is a deuterium-labeled variant of Robenidine hydrochloride, an anticoccidial agent. It demonstrates activity against MRSA and VRE, with MIC50s of 8.1 and 4.7 μM, respectively. This compound is designed for laboratory use, primarily as a tracer and an internal standard for quantitative analysis in techniques such as NMR, GC-MS, or LC-MS.
- Deuterium-labeled compound
- Anticoccidial agent
- Active against MRSA and VRE
- Suitable for quantitative analysis
- Can be used as a tracer
- Functions as an internal standard
Medchemexpress LLC Tryptamine-d2 hydrochloride | 362049-48-7 | 99.9% | 1 MG
Tryptamine-d2 (hydrochloride) is a deuterium labeled Tryptamine hydrochloride. Tryptamine hydrochloride is a monoamine alkaloid, similar to other trace amines, and is believed to play a role as a neuromodulator or neurotransmitter. This compound is for research use only and is not sold to patients.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Phenothiazine-d8 | 1219803-41-4 | 99.0% | 207.32 | C12HD8NS | 10mg
Phenothiazine-d8 is the deuterium labeled Phenothiazine Phenothiazine is an antibiotic which has insecticidal fungicidal antibacterial and anthelmintic activities Phenothiazine also can be used for the research of neurological diseases[1][2]